Viruses, close enemies or distant cousins?

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0mommmmy.jpgThe advance of biological engineering allows scientists to manipulate genes and modify the very nature of certain organisms. Some of these applications have the potential to change the way we relate to the microscopic elements such as viruses. Viruses appear to be nasties whose sole purpose is to infect and make our lives miserable. However, certain viruses can make us stronger.

Chickenpox, for example, holds a choice or a strong division of opinions. Some people believe that natural immunity can be a better defence than a medical vaccine. So catching the virus could become a deliberate act of invoking your own immune system’s protection.

In a project titled "Viruses, close enemies or distant cousins?" and shown at the Design Interactions Work in Progress Show, Mikael Metthey has tried to explore the social consequences of a shift in the perceptions and the applications of viruses.

In the same way as some parents would feed their kids with organic food, they might want them to be infected by chickenpox in a carefully controlled way. Mikael's scenario envisions how it could go.

A laboratory he calls Varilab would manipulate the chickenpox virus so that it would be less aggressive to the human body. It would then be made available to parents who belive that natural immunity is best for their child. The viruses would be stored and labelled according to their age and concentration. They would also be designed not to survive beyond ten minutes to avoid any uncontrolled pandemics. The virus would then be kept inside pressurised capsules, and the parents would release it to infect a toy (the lovely Pox Teddy), the child would thus play and get a mild infection that ensure that he or she doesn't catch chickenpox in adulthood (which can be pretty annoying as some my testify ;-)

0poxteddy.jpg

Mikael's presentation featured a few more interesting questions such as How might we interact with viruses in the future?; How shall we consume them? Could you imagine that one day you'd keep every virus you've ever had in your life as memories? Or display them as a demonstration of your social status?

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4 Comments:

Viral insignia heh :)

On a bacterial level this all is old news of course. Everybody gulps down Lactobacillae and other bacterial cultures like their life depends on it.

Oh wait, it does!

What about the work of Edward Jenner? Before inoculation with vaccines, wasn't cowpox actually discovered and then used to immunize against smallpox?

Simon Restrepo

Hmm... The usual way of making vaccines is to make weaker versions of the original pathogens (Pasteur and Jenner started this a while ago). Someone is re-inventing the wheel here. Nowadays when it is not possible to make a weak pathogen, recombinant genetics are used to produce parts of the virus that will be used as a vaccine in order to trigger acquired immunity. This is the same as natural immunity. We have a certain degree of inborn immunity but only against some bacteria and not against viruses.
Besides the most interesting aspect of viruses nowadays is how they can be used as DNA delivery vectors for gene therapy. Most of the curent gene therapy protocols involve engineered forms of viruses such as HIV.
Oh coming back to bacteria, we have 1.5 kg of bacteria living in our gut. Actually we have more bacterial than human cells in our body!
Hope someone finds this information useful.
Cheers
Simon

kjs3

You guys must not have kids. Parents have been deliberately exposing their child to chickenpox at least since I was a kid (40 years). Google for "chickenpox party".

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